Chapter 3 - Beyond the Central Dogma

THE APPLICATIONS OF MULTIOMICS RESEARCH EXTEND FAR BEYOND

THE CENTRAL DOGMA. MULTIMODAL TECHNIQUES ARE BEING

USED TO MAP THE SECRETOME, INTERACTOME AND HOLOGENOME,

AMONGST OTHERS. THIS CHAPTER EXPLORES THE POSSIBILITIES

OF MULTIOMICS RESEARCH AT A SYSTEMS BIOLOGY LEVEL, FROM

HOW ENDOPHENOTYPE RESEARCH IS BRIDGING SCALES BETWEEN

MOLECULES AND PHENOTYPES, TO HOW MULTIMODAL ANALYSIS OF

THE EXPOSOME CAN SHED LIGHT ON THE BIOLOGICAL IMPACT OF AN

INDIVIDUAL’S ENVIRONMENT.