In this episode, we explore the pharmacologic management of major endocrine disorders, focusing on thyroid and adrenal dysfunction as well as the emergency treatment of diabetic crises. We’ll review the clinical features of hyperthyroidism and hypothyroidism, examining therapies such as levothyroxine for hormone replacement and propylthiouracil (PTU) for reducing excessive thyroid hormone production. The discussion then shifts to adrenocortical agents used in conditions like Addison’s disease and Cushing’s syndrome, emphasizing the delicate balance required to maintain physiologic stability.

We’ll also break down the critical management of Diabetic Ketoacidosis (DKA) and Hyperglycemic Hyperosmolar Syndrome (HHS) ...