In this riveting episode, Dr. Brujic delves into the fascinating world of particle self-assembly. We discuss a groundbreaking model system of colloidal droplet chains that leverage programmable DNA interactions to direct their folding into distinct geometries. As Dr. Brujic explains, it is possible to watch these droplets in real time and space, enabling researchers to unravel the rules of folding.

Dr. Brujic describes the power of controlling the order in which interactions occur to guide folding into unique structures, termed "colloidal foldamers." We examine the capabilities of simple alternating sequences and explore how these sequences create a variety of foldamers in both two and three dimensions.

By optimizing droplet sequence and adding an extra 'flavor', researchers are able to encode a significant portion of the 619 possib ...