In this intriguing episode, we welcome Dr. Gäbelein, a scientist at the forefront of cell biology, as he introduces us to a revolutionary approach for manipulating organelle structures within single live cells. This technique, based on FluidFM, involves atomic force microscopy, optical microscopy, and nanofluidics to achieve precision in force and volume control and provides real-time examination capabilities.

Dr. Gäbelein walks us through the process of developing this innovative technology, highlighting the role of specially designed probes that facilitate minimal invasive entry into cells. He further elaborates on how optimizing fluid flow allows for the extraction of specific organelles.

Dr. Gäbelein shares fascinating findings from his study, particularly the transformation of mitochondria into a pearls-on-a-string phenotype when ...