Uma Thurman as Beatrix "the Bride" Kiddo

Lucy Liu as O-Ren Ishii (code name Cottonmouth)

Vivica A. Fox as Vernita Green (code name Copperhead)

Daryl Hannah as Elle Driver (code name California Mountain Snake)

Michael Madsen as Budd (code name Sidewinder)

Sonny Chiba as Hattori Hanzō

Julie Dreyfus as Sofie Fatale

Chiaki Kuriyama as Gogo Yubari

David Carradine as Bill (code name Snake Charmer