96 - Controlled Release & Targete...

96 - Controlled Release & Targeted Delivery (S7E6)

From Concept to Medicine - A Comprehensive Drug Development ... por Jim Mitchell

Notas del episodio

This episode explains how controlled release and targeted delivery systems optimize therapeutic outcomes and minimize side effects. It explores the use of polymer-based systems as tiny time-release capsules for drugs, and discusses mechanism-driven designs that utilize specific triggers in the body to release medication where it's needed. Real-world examples from research papers, particularly OPR&D publications, illustrate the principles behind these technologies. The episode emphasizes the advantages of these systems over traditional drug delivery methods.

Beyond simply administering medication, controlled release and targeted delivery aim for precise control over drug release and distribution within the body. The episode highlights the importance of achieving consistent drug levels within the therapeutic window, avoiding fluctuations  ... 

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