92 - Excipients: Roles and Selection (S7E2)
From Concept to Medicine - A Comprehensive Drug Development ... por Jim Mitchell
Notas del episodio
This episode delves into the critical role of excipients, the inactive ingredients in medications, in drug formulation. It explains how these often-overlooked components are carefully chosen to enhance stability, delivery, and patient acceptability. The episode explores the various functions of excipients, from stabilizing the API to aiding in its dissolution and absorption in the body. It discusses how excipients can be tailored to specific patient groups, such as children or individuals with difficulty swallowing, to optimize drug delivery and safety. Real-world case studies are used to illustrate the impact of excipient choices on formulation performance.
Beyond simply acting as fillers, excipients play a vital role in ensuring a medicine's effectiveness and safety. They can protect the API from degradation, improve its solubility, and c ...