How does the brain build an internal map of space , and what happens when that map is slightly wrong? Nobel laureate Edvard Moser describes the discovery of grid cells, their modular organization, and the surprising geometric distortions that reveal how the brain calibrates its spatial metric against the physical world. Subscribe for more from the Convergent Science Network podcast series. Edvard Moser joins Paul Verschure and Tony Prescott at the BCBT summer school to discuss his research on the neural basis of spatial navigation. The conversation traces the path from hippocampal place cells to the discovery of grid cells in the medial entorhinal cortex , neurons that fire in strikingly regular hexagonal patterns as an animal moves through space. Moser explains how targeting electrodes to a more dorsal region of entorhinal cortex, guided by neur ...