Can orthobiologics outperform steroids in equine osteoarthritis treatment?

In Episode 11 of Sit. Stay. Learn., Dr. Adrienne Wright reviews the 2020 paper “Effects of Autologous Conditioned Serum, Autologous Protein Solution, and Triamcinolone on Inflammatory and Catabolic Gene Expression in Equine Cartilage and Synovial Explants Treated with IL-1β in Co-culture” and breaks down how ACS, APS, and triamcinolone compare in an inflamed joint model.

In this episode, she covers: • what autologous conditioned serum (ACS) and autologous protein solution (APS) are • how these orthobiologics compare to triamcinolone • what the study found about inflammatory gene expression • why PGE2 reduction matters in equine OA • and what this could mean for managing lameness and joint disease in horses

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